SPACE FRAME
Easier and quicker to build.
Not as torsionally rigid for a given weight. In other words, less strength to weight ratio.
Less tools required to build.
Not "correct" as a replica.
Materials probably a little more expensive if you count the aluminum sheet usually used for cladding.
MONOCOQUE
More difficult and time consuming to build.
More torsional rigidity for a given weight. Better strength to weight ratio.
More tools required to build.
Correct chassis as far as a replica.
Materials required probably less expensive unless you do it in aluminum.
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use the search function and enter "monocoque", "search all open forums" there's lots of stuff