This is one of those questions that there is no single "best" answer for.
What I mean by this is that the best transaxle for one person might not be the best choice for you.
Choosing major components such as the engine, trans, and even the car itself,,,, first you need to ask yourself some questions.
#1: what is the primary use for the car?
#2: how concerned am I about "originallity"?
#3: what is my budget?
I'll use my car as an example.
It is to be primarily a street driven car with some occaissonal track use. I am building a mild 302, which should be just under 400hp. I am not concerned with having an "authentic" gearbox, since I am not building a 100 percent "clone" of an original car.
I am using a Renault box, because the gear ratios are favorable for the car. I can install a HD input shaft & drive axle flanges for a durable setup. This box has been proven for many years in other GT40 replicas. The available bellhousing has enough room for a stock sized 10.5 inch ford replacement clutch assembly, which is much more affordable than buying custom clutches needed for other set ups. (I always want my clutch assembly to be the "weakest link" in my drivetrain, since clutches are cheaper than gearboxes.... being able to buy a ford 10.5 inch replacement means they are easy to find and inexpensive.)
I'm not saying the Renault is the best choice for everyone, but I do belive that it will fit my requirements very well.
Now, if I get the chance to build a 500 plus horsepower screamer for my car, I will probably be looking into a more serious transaxle to go along with it.....
...but since I have to repair cars everyday for a living,,,, I am much happier with a dependable "tame" car to play with, than I am with a high strung racing motor on the street. I find that I can spend much more time "driving" and enjoying a car when I'm not always fixing broken parts.