Engine numbers

Can anyone tell me what the difference is between the following engine numbers:
C8TE-6015-B
3H221080
I assume the 1st one is the engine block casting number but I a baffled as to the significance of the latter.
3H221080 is the number stamped on the rear L/H side of the engine block infront of the inlet header.
Any help greatly appreciated.
 
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