Where is the simplicity in this? These countries WILL develop the bomb sooner or later, with or without our sanctions. If the US had a stellar record of it's interventions into other country's internal affairs, we'd have a reputable leg to stand on.
As it stands, the last time we invaded a country for WMD (a sovereign country which was no threat to homeland), or tried to tell them their business, we basically opened Pandora's box and destroyed any constraints to organizations resembling ISES.
Making things worse, bending over and spreading every time Netanyahu opens his zipper is a disgrace of independent thinking from our own politicians. The sooner we quit enabling Israel, the sooner they will start to become the solution rather than contributing to the problem.