The cammer motors already have a huge following, in Mustangs, Lightnings, and regular trucks. Parts are a plenty and cheap. A lot of the "blown up mod motors" are of the Lightning and 03/04 Cobra supercharged design where idiots crank up the boost without doing anything else. But, there have been a large number of NA failures in the pre-03 Cobras too.
Still, you can't beat the pushrod motor for weight, power, and price. The mod motors are just too dang big. Why, pray tell, do I need SOHC designs on the 5.4 long stroke truck motor so that it can have a 5200 RPM red line?
The question, however, is answered in that they do fit and can be made to work. But, I would counter that if you used a pushrod motor, used ALL the smog stuff (air injection into the heads, EGR, not to mention cats, etc.) as intended they'll pass smog too. Lynn has one setup with the OEM electronics and sensors and if it had cats I bet it'd pass with no trouble. Lot easier than doing the same on the mod motor.
R