John --
Although the shop I'm about to move into is not as big, it's about the same shape; I'm wondering what thoughts you've had about laying it out. Do you have any sketches or floorplans showing where you are going to put various things? In my case the items fall into some obvious categories, like toolboxes and small power equipment (eg angle grinder), parts and supplies, metal working machines (grinders, mill, bandsaw, lathe), wood working machines (table saw, planer), 2-post lift, compressor, etc.