Dean, I'll give you my opinion. I was running Wayne's Very Cool Parts EFI stacks on a 392 Ford crate engine (430 HP advertised) in my coupe. It is a speed density system that has a common vacuum plenum in the manifold that feeds the sensor in the computer. The ECU was a Redline 882 system that controlled both fuel and spark. The fuel map is vacuum over RPM and has an infinite amount of tunability. It even has the ability to vary the ratio of fuel enrichment over the rpm curve driven by TPS vs. the fuel map. This allows you to tune for the typical challenges that a stack style SD set up has where you are at high rpm with the throttle plates open and you suddenly brake, snapping the throttle plates closed and low rpm with the throttle plates closed and you floor it. Anyway, the amount of options and flexibility of the system can be daunting. My at the time 13 yo son and I drove the car around for many, many hours with the wideband connected and the ecu in open loop, fine tuning the fuel curve on the laptop and got it pretty well set. It was phenominal at low to mid-range with wonderful throttle response. It wasn't as potent on the top end. I never had it on a dyno, but judging by seat of the pants and experience this was the case.
Now the reason I know this is that one day the car started running like crap. I hooked up the wideband and the afr was jumping all over the place 5:1 to 20:1 with no apparent reason. I spent days troubleshooting it and finally one weekend in a fit of frustration, removed it and installed a single plane manifold and Holley 750DP. I can tune a Holley carb and we had it running great in a few hours. It didn't have the same excellent throttle response the stacks had, but at wot over about 2500 rpm, it was unbeatable.
Okay, a long story, but one of the things I liked about the Redline ECU was that the tunning parameters and controls were very similar to tunning a carb. It had an acceleration circuit that you could control amount, duration , and sensitivity. The fuel map was the same as jets on a carb, but it was as if you could control the size at every rpm and manifold pressure. It had additional controls to compensate for outside temperature, coolant temperature, and altitude. The biggest issue I had with it once I got used to how it worked and how to tune it was the complexity and difficulty of troubleshooting when something went wrong.
I hope that is helpful!